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SKU: E-AB-70253_60μL-ES
PPARA Polyclonal Antibody, 60 μL
Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that belongs to the PPAR nuclear receptor superfamily. PPARA is essential in the modulation of lipid transport and metabolism, mainly through activating mitochondrial and peroxisomal fatty acid β-oxidation pathways. In addition, PPARA seems to decrease inflammation mainly through direct interaction with NF-κB, causing inhibition of its signaling pathway or reducing the activated levels of NF-κB and subsequent inflammation. Furthermore, PPARA was implicated in the attenuation of oxidative stress in alcoholic liver disease when treated with polyenephosphatidylcholine through downregulation of ROS-generating enzymes such as ethanol-inducible cytochrome P450 2E1 (CYP2E1), acyl-CoA oxidase, and NADPH oxidase.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.6 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:200-1:500
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Application:IHC
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Research Areas:Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Species Reactivity:Mouse; Rat
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Target Synonym:hPPAR;MGC2237;MGC2452;NR1C1;Nuclear receptor subfamily 1 group C member 1;OTTHUMP00000197740;OTTHUMP00000197741;Peroxisome proliferative activated receptor alpha;Peroxisome proliferator activated receptor alpha;Peroxisome proliferator-activated receptor alpha;PPAR;PPAR-alpha;ppara;PPARA;PPARalpha
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Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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