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SKU: E-AB-16045_200μL-ES
PTPRM Polyclonal Antibody, 200 μL
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1.1 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:100-1:300
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Application:IHC
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Research Areas:Signal Transduction
Species Reactivity:Human;Mouse
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Target Synonym:hR PTPu;Protein tyrosine phosphatase mu;Protein tyrosine phosphatase receptor type M;Protein tyrosine phosphatase receptor type mu polypeptide;Protein-tyrosine phosphatase mu;PTPRL1;Ptprm;PTPRM;R PTP mu;R-PTP-mu;Receptor type tyrosine protein phosphatase mu;Receptor-type tyrosine-protein phosphatase mu;RPTPM;RPTPU
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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