- Specification
- Downloads
- Reviews
€247,50
ADD TO CART
BT LAB
SKU: BT-AP04380-100ul
RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 100ul
Catalytic activity:Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.|Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double| nick| or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. RAD9A possesses 3'->5' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.|PTM:Constitutively phosphorylated on serine and threonine amino acids in absence of DNA damage. Hyperphosphorylated by PRKCD and ABL1 upon DNA damage. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.|Belongs to the rad9 family.|subunit:Component of the toroidal 9-1-1 (RAD9-RAD1-HUS1) complex| composed of RAD9A| RAD1 and HUS1. The 9-1-1 complex associates with LIG1| POLB| FEN1| RAD17| HDAC1| RPA1 and RPA2. The 9-1-1 complex associates with the RAD17-RFC complex. RAD9A interacts with BCL2L1| FEN1| PRKCD| RAD9B| HUS1| RAD1| ABL1| RPA1| ATAD5 and RPA2.|
- Regular price
- €247,50 EUR
- Sale price
- €247,50 EUR
- Regular price
-
ADD TO CART
Product Specification
Basic Information
Brands:BT LAB
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:1 mg/ml
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:
Observed Molecular Weight:
Purity:
Shelf Life:
Storage:-20°C for 1 year
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:
Dilution:
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Features and Capabilities
Application:WB, ELISA
Detection Target:RAD9
Detection Type:
Detection Range:
Research Areas:Epigenetics and nuclear signaling
Species Reactivity:
Reactivity:Human, Rat, Mouse
Target Synonym:
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:
Bottom Shape:
Bottom Type:
Buffer:
Cap Color:
Clonality:Polyclonal
Conjugation:
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Graduation:
Growth Area: