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SKU: E-AB-52783_120μL-ES
RBM15 Polyclonal Antibody, 120 μL
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:30-1:150
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Application:IHC
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Research Areas:Epigenetics and Nuclear Signaling;Stem Cells
Species Reactivity:Human
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Target Synonym:One twenty two protein;One-twenty two protein 1;OTT;OTT1;Putative RNA-binding protein 15;RBM15;RBM15;RNA binding motif protein 15;RNA-binding motif protein 15
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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