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SKU: E-AB-81574_50μL-ES
Recombinant Integrin beta 5 Monoclonal Antibody, 50 μL
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:300 μg/mL
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Calculated Molecular Weight:88kDa
Observed Molecular Weight:88kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:88kDa
Dilution:WB 1:500-1:1000
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Application:WB
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Research Areas:Cancer; Signal Transduction
Species Reactivity:Human; Rat; Hamster
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Target Synonym:FLJ26658;Integrin beta-5;Integrin subunit beta 5;integrin;beta 5;ITB5;Itgb5;Testis secretory sperm-binding protein Li 217p
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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