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SKU: E-AB-81579_100μL-ES
Recombinant LRP1 Monoclonal Antibody, 100 μL
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Technical Specifications
Capacity:
Concentration:300 μg/mL
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Calculated Molecular Weight:85kDa
Observed Molecular Weight:85kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:85kDa
Dilution:WB 1:1000-1:2000;IHC 1:20-1:100
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Features and Capabilities
Application:WB;IHC-P
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Research Areas:Neuroscience; Cardiovascular; Cell Biology; Signal Transduction; Metabolism; Cancer
Species Reactivity:Human; Mouse; Rat
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Target Synonym:LRP1;A2MR;APOER;APR;CD91;IGFBP3R;KPA;LRP;LRP1A;TGFBR5
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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