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SKU: E-AB-81441_100μL-ES
Recombinant TGF beta 1 Monoclonal Antibody, 100 μL
TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Technical Specifications
Capacity:
Concentration:300 μg/mL
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Calculated Molecular Weight:44kDa
Observed Molecular Weight:44kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:44kDa
Dilution:WB 1:500-1:1000
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Application:WB
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Species Reactivity:Human; Mouse; Rat
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Target Synonym:TGF beta 1;TGFB;CED;LAP
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Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
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Clonality:Rabbit Monoclonal
Conjugation:Unconjugated
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