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SKU: E-AB-52117_60μL-ES
ROCK2 Polyclonal Antibody, 60 μL
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Calculated Molecular Weight:161 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:161 kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Cell Biology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:coiled-coil-containing protein kinase 2;KIAA0619;p164 ROCK 2;p164 ROCK-2;Rho associated coiled coil containing protein kinase 2;Rho associated protein kinase 2;Rho associated;coiled coil containing protein kinase II;Rho kinase 2;Rho-associated;Rho-associated protein kinase 2;ROCK 2;Rock II;Rock2;ROCK2;Rock2m;ROK alpha;ROKalpha
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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