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SKU: E-AB-30103_120μL-ES
RUNX2 Polyclonal Antibody, 120 μL
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:57kDa
Observed Molecular Weight:56kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:57kDa
Dilution:WB 1:500-1:2000;IF 1:50-1:200
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Application:WB;IF
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Developmental Biology;Stem Cells
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Acute myeloid leukemia 3 protein;Alpha subunit 1;AML3;CBF alpha 1;CBF-alpha-1;CBFA1;CCD;CCD1;Cleidocranial dysplasia 1;Core binding factor;Core binding factor runt domain alpha subunit 1;Core binding factor subunit alpha 1;Core-binding factor subunit alpha-1;MGC120022;MGC120023;Oncogene AML 3;Oncogene AML-3;OSF 2;OSF-2;OSF2;Osteoblast specific transcription factor 2;Osteoblast-specific transcription factor 2;OTTHUMP00000016533;PEA2 alpha A;PEA2-alpha A;PEA2aA;PEBP2 alpha A;PEBP2-alpha A;PEBP2A1;PEBP2A2;PEBP2aA;PEBP2aA1;Polyomavirus enhancer binding protein 2 alpha A subunit;Polyomavirus enhancer-binding protein 2 alpha A subunit;Runt domain;Runt related transcription factor 2;Runt-related transcription factor 2;RUNX2;RUNX2;SL3 3 enhancer factor 1 alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit;SL3/AKV core binding factor alpha A subunit;SL3/AKV core-binding factor alpha A subunit
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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