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SKU: E-AB-32840_20μL-ES
RYR2 Polyclonal Antibody, 20 μL
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:564kDa
Observed Molecular Weight:200-300kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:564kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000
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Application:WB;IHC-p;IF
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Research Areas:Cancer;Cardiovascular;Metabolism;Neuroscience;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:ARVC2;ARVD2;Cardiac muscle ryanodine receptor;Cardiac muscle ryanodine receptor-calcium release channel;hRYR-2;ryanodine receptor 2 (cardiac);Ryanodine receptor 2;RyR;RYR-2;RyR2;RYR2;Type 2 ryanodine receptor;VTSIP
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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