BT LAB

SKU: BT-AP12363-50ul

S12A3 Rabbit Polyclonal Antibody, 50ul

This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome| a disease similar to Bartter's syndrome| that is characterized by hypokalemic alkalosis combined with hypomagnesemia| low urinary calcium| and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Application:WB

Detection Target:SLC12A3

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Research Areas:Cardiovascular; Signal transduction; Metabolism

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Reactivity:Human, Mouse, Rat

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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