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SKU: E-AB-15382_20μL-ES
SEMA4A Polyclonal Antibody, 20 μL
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.8 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:30-1:150
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Application:IHC
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Research Areas:Cancer;Cardiovascular;Neuroscience
Species Reactivity:Human
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Target Synonym:CORD10;RP11 54H19 2;RP35;SEM4A;Sema B;Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain 4A;Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4A;Sema domain;immunoglobulin domain (Ig);transmembrane domain (TM) and short cytoplasmic domain;(semaphorin);Sema4a;SEMAB;Semaphorin 4A precursor;Semaphorin B;Semaphorin-4A;Semaphorin-B;SEMB
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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