BT LAB

SKU: BT-AP07944-50ul

Separase(Phospho Ser801) Polyclonal Antibody, 50ul

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates| sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1| or separase| which initiates the final separation of sister chromatids (Sun et al.| 2009

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Technical Specifications

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, IHC-p, IF, ICC, ELISA

Detection Target:ESPL1

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Research Areas:Cell biology; Epigenetics and nuclear signaling

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Reactivity:Human, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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