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SKU: E-AB-15853_200μL-ES
SMAD7 Polyclonal Antibody, 200 μL
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.4 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Signal Transduction
Species Reactivity:Human;Mouse;Rat
Reactivity:
Target Synonym:CRCS3;FLJ16482;hSMAD 7;hSMAD7;MAD (mothers against decapentaplegic Drosophila) homolog 7;MAD;Mad homolog 7;MAD homolog 8;MAD mothers against decapentaplegic homolog 7;MADH 7;MADH 8;MADH6;MADH8;Mothers Against Decapentaplegic Drosophila Homolog of 6;Mothers Against Decapentaplegic Drosophila Homolog of 7;Mothers against decapentaplegic homolog 7;Mothers against decapentaplegic homolog 8;Mothers against DPP homolog 7;Mothers against DPP homolog 8;SMA- AND MAD-RELATED PROTEIN 7;SMAD 7;SMAD;SMAD family member 7;SMAD;mothers against DPP homolog 7 (Drosophila);SMAD;mothers against DPP homolog 7;SMAD6;Smad7;SMAD7
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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