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SKU: E-AB-52997_20μL-ES
SORBS2 Polyclonal Antibody, 20 μL
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Calculated Molecular Weight:124 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:124 kDa
Dilution:WB 1:1000-1:5000;IHC 1:150-1:300
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Application:WB;IHC
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Research Areas:Signal transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Arg binding protein 2;Arg-binding protein 2;Arg/Abl interacting protein 2;Arg/Abl interacting protein;Arg/Abl-interacting protein 2;ArgBP2;KIAA0777;PRO0618;sorbin and SH3 domain containing 2;Sorbin and SH3 domain-containing protein 2;Sorbin;Sorbs2;SRBS2
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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