SKU: E-AB-92884_200μL-ES

TNFSF8 Polyclonal Antibody, 200 μL

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:26kDa

Observed Molecular Weight:46kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:26kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Immunology

Species Reactivity:Human;Mouse;Rat

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Target Synonym:TNFSF8;CD153;CD30L;CD30LG;TNLG3A

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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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