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SKU: E-AB-92874_200μL-ES
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TOP3B Polyclonal Antibody, 200 μL
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Technical Specifications
Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:79kDa/82kDa/96kDa
Observed Molecular Weight:120kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:79kDa/82kDa/96kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Epigenetics and Nuclear Signaling
Species Reactivity:Human;Rat
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Target Synonym:TOP3B;TOP3B1
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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