Total Bilirubin (TBIL) Assay Kit,50T

Brands:Solarbio

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Place of Origin:China

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Shipping:Ice bag

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Shelf Life:6 months under -20℃

Storage:-20℃

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Research Areas:Other Biochemical Series

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Total Bilirubin (TBIL) is the sum of direct bilirubin and indirect bilirubin. Indirect bilirubin is poorly soluble in water and cannot be excreted by the kidneys. Within hepatocytes ， it combines with glucuronic acid to form direct bilirubin; direct bilirubin is water-soluble and can be excreted through the kidneys in urine. The liver is responsible for the uptake ， conjugation ， and excretion of bilirubin. Total bilirubin serves as a crucial indicator of liver function and is the primary basis for diagnosing jaundice ， aiding in the diagnosis of liver/biliary diseases and blood disorders.

Under acidic conditions ， indirect bilirubin is converted to direct bilirubin with the aid of the accelerator CTAB. Direct bilirubin reacts directly with the diazonium reagent (chlorinated diazobenzene sulfonic acid formed from p-aminobenzenesulfonic acid and sodium nitrite) to produce a purple-red azo compound. This compound exhibits a characteristic absorption peak at 530 nm. enabling the calculation of total bilirubin concentration.

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