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SKU: E-AB-10661_120μL-ES
TPM1 Polyclonal Antibody, 120 μL
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.1 mg/mL
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Calculated Molecular Weight:33kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:33kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200
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Application:WB;IHC
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Research Areas:Cancer;Cardiovascular;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:AA986836;AI854628;Alpha tropomyosin;alpha-TM;Alpha-tropomyosin;C15orf13;cardiomyopathy;hypertrophic 3;CMD1Y;CMH3;HTM alpha;HTM-alpha;OTTHUMP00000163688;sarcomeric tropomyosin kappa;TM2;Tmpa;TMSA;Tpm-1;TPM1;TPM1;tropomyosin 1 (alpha);tropomyosin 1 (alpha) isoform 1;tropomyosin 1 (alpha) isoform 2;tropomyosin 1 (alpha) isoform 3;tropomyosin 1 (alpha) isoform 4;tropomyosin 1 (alpha) isoform 5;tropomyosin 1 (alpha) isoform 6;tropomyosin 1 (alpha) isoform 7;Tropomyosin 1;Tropomyosin alpha 1 chain;Tropomyosin alpha-1 chain;Tropomyosin;skeletal muscle alpha;Tropomyosin-1
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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