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SKU: E-AB-91044_120μL-ES
VAV1 Polyclonal Antibody, 120 μL
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1mg/mL
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Calculated Molecular Weight:94kDa/98kDa
Observed Molecular Weight:95KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:94kDa/98kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:VAV1;VAV
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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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