SKU: E-AB-91047_120μL-ES

Y14/RBM8A Polyclonal Antibody, 120 μL

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:19kDa

Observed Molecular Weight:20kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:19kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Epigenetics and Nuclear Signaling

Species Reactivity:Human;Mouse;Rat

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Target Synonym:RBM8A;BOV-1A;BOV-1B;BOV-1C;C1DELq21.1;DEL1q21.1;MDS014;RBM8;RBM8B;TAR;Y14;ZNRP;ZRNP1

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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