SKU: E-AB-91990_120μL-ES

ZFPM1 Polyclonal Antibody, 120 μL

Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Capacity:

Concentration:1mg/mL

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Calculated Molecular Weight:104kDa

Observed Molecular Weight:105KDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:104kDa

Dilution:WB 1:500-1:2000;IF 1:50-1:200

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Application:WB;IF

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Research Areas:Epigenetics and Nuclear Signaling;Neuroscience;Cardiovascular

Species Reactivity:Human;Mouse;Rat

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Target Synonym:FOG;FOG1;ZNF408;ZNF89A;ZC2HC11A;ZFPM1

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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